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MAVEn™高通量16通道果蠅代謝監(jiān)測系統(tǒng)
果蠅作為經(jīng)濟(jì)實(shí)用的模式動(dòng)物,可用于中樞神經(jīng)系統(tǒng)紊亂、炎癥性病變、心血管疾病、癌癥以及糖尿病等治療研究,而這些疾病的發(fā)生從生理上來說都與生物個(gè)體長期的代謝功能異常密切相關(guān)。
MAVEn™高通量16通道果蠅代謝監(jiān)測系統(tǒng)是由世界知名的美國Sable Systems International動(dòng)物代謝測量公司生產(chǎn)的一款16通道、高分辨率及自動(dòng)化的果蠅代謝監(jiān)測儀器,可廣泛用于代謝紊亂造成的各種流行疾病治療的機(jī)理研究。
MAVEn™果蠅代謝系統(tǒng)作為果蠅代謝分型監(jiān)測方面的權(quán)威產(chǎn)品,主要具備以下特點(diǎn):
1. 改變了傳統(tǒng)的單只果蠅的封閉或半封閉式測量模式,實(shí)現(xiàn)每個(gè)測量室都有實(shí)時(shí)氣
流通過的完全開放式測量,避免了測量時(shí)內(nèi)出現(xiàn)缺氧(hypoxia)或高碳酸血癥
(hypercapnia),可一次測量多達(dá)16只個(gè)體。
2. 15秒就可以完成一只果蠅的代謝監(jiān)測,這代表了目前技術(shù)的**水平。
3. 數(shù)據(jù)可以通過SD卡把帶時(shí)間標(biāo)簽的CSV格式直接導(dǎo)出到電腦。
4. 可選配FLIC果蠅覓食、AD-2果蠅活動(dòng)、氣體(氧氣、二氧化碳、水汽以及其它可
檢測氣體)等監(jiān)測單元。
5. 參考文獻(xiàn)*多,高達(dá)4萬多篇,屬于前沿科技。
具體性能指標(biāo):
1. 氣流流速:5毫升/分鐘-200毫升/分鐘,質(zhì)量流量計(jì),PID精確控制,精度為2%。
2. 昆蟲測量時(shí)間:15秒-3小時(shí)可程序化選擇;基線測量時(shí)間:15秒-3小時(shí)可程序
化選擇。
3. 氣壓測量:分辨率1Pa,精度0.05%。
4. 光照水平:0.1-5000勒克斯。
5. 溫度測量:0-50℃,分辨率0.01℃,精度±0.25℃。
6. 模擬輸入:6個(gè)模擬輸入,16bit分辨率,-5至+5伏電壓信號(hào),可接SSI其它儀器
或?qū)嶒?yàn)室其它氣體分析儀等。
7. 數(shù)據(jù)格式:CSV格式;數(shù)據(jù)存儲(chǔ):SD卡,**支持32G的SD卡。
8. 雙通道高精度差分式氧氣分析測量儀:測量技術(shù):燃料電池原理氧氣傳感器,
雙通道;氧氣濃度量程0-100%(用戶可自定義設(shè)置5個(gè)級(jí)別);差值量程±50%;
精度0.1%(O2濃度2-100%時(shí));分辨率0.0001%O2;漂移< 0.01%每小時(shí)(溫度
恒定情況下);響應(yīng)時(shí)間小于7秒;24小時(shí)漂移<0.01%;20分鐘噪音<3ppm RMS;
數(shù)字過濾(噪音)0-40秒可調(diào),增幅0.2秒,內(nèi)置A/D轉(zhuǎn)換器分辨率16bits;溫
度、壓力補(bǔ)償;傳感器溫度測量范圍0-60℃,精度0.2℃,分辨率0.001℃;大
氣壓測量分辨率0.0001kPa,精度為滿量程的0.05%;適用流量范圍5-2000mL/
min;4通道模擬信號(hào)輸出(0-5V BNC)可輸出通道1的氧氣濃度,通道2的氧氣
濃度,1和2的差值,大氣壓;數(shù)字輸出:RS-232;具4行文字LCD顯示屏,帶背
光,可同時(shí)顯示2個(gè)通道的氧氣含量和它們的差值,以及大氣壓;獨(dú)具PID
(Proportional-Integral-Derivative)溫控單元,保證內(nèi)部氧氣傳感器溫度恒
定,進(jìn)一步提高了氧氣測量的精度和穩(wěn)定性;供電12-24VDC,8A,配交流電適
配器;工作溫度:5-45℃,無冷凝;重量6.4kg;尺寸43.2cm×35.6cm×20.3cm
9. 超高精度二氧化碳分析測量儀:用于測量微小昆蟲(比如果蠅、蚊子等)或蜱
螨類微小動(dòng)物的呼吸代謝,可同時(shí)測量CO2濃度和H2O濃度;CO2量程0-3000ppm;
準(zhǔn)確度<1%;分辨率0.01ppm;H2O量程0-60mmol/mol;準(zhǔn)確度1%;
10. 二次抽樣單元:內(nèi)置氣泵、精密針閥、質(zhì)量流量計(jì),可用來給氣流樣本做二次
抽樣,也可單獨(dú)作為氣源使用;流量范圍5-2000mL/min;精度為讀數(shù)的10%;
分辨率1mL/min;具備2行顯示LCD顯示屏;帶0-5V BNC模擬信號(hào)輸出;數(shù)字輸
出RS-232;供電12-15VDC,20-350mA,配交流電適配器;工作溫度:0-50℃,
無冷凝;重量1.5kg;尺寸16cm×13cm×20cm;
產(chǎn)地:美國
文獻(xiàn)案例:
在2016年已發(fā)表的果蠅有關(guān)文獻(xiàn)中,使用SSI果蠅代謝監(jiān)測系統(tǒng)的達(dá)14篇,2015年11篇,截止目前相關(guān)文獻(xiàn)共計(jì)500多篇。
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